Power in Numbers
If you have a large room with more than one sitting area, it's perfectly acceptable to use more than one area rug.
Cover Walking Area
In any hallways or high-traffic areas, try adding an area rug runner. Make sure it's wide enough to walk comfortably.
Small Room, More Rug
If you have a small room, try adding an area rug that almost covers the entire floor - except for a few inches.